• NEWEST by Mastelli

    GLOWING YOUNGER
    with immediate lifting & hydration

NEWEST by Mastelli

If you want hydrated, youthful skin, try the NEWEST by Mastelli treatment at Cocoon Medical Spa. Right away, this injectable gel fuses polynucleotides, hyaluronic acid, and mannitol for an instant glow. Moreover, it works deep within to rebuild firmness and smooth fine lines. Consequently, your skin feels plumper and more vibrant after each session.

What It NEWEST by Mastelli

NEWEST is a patented injectable gel from Mastelli Aesthetic in Italy. It combines PN‑HPT™ polynucleotides, hyaluronic acid, and mannitol in one precise formula. Together, these elements lock in moisture, power up your skin’s renewal, and shield against damage. In fact, hyaluronic acid boosts PN‑HPT™’s fibroblast stimulation by 20%, while mannitol slows HA breakdown by 30%.

Polynucleotide treatments have long helped medical healing, and now aesthetics benefit too. Mastelli sources DNA from selectively bred trout. Once injected into the dermis, these fragments spark collagen and elastin production at a cellular level. As a result, tissue regeneration improves and overall skin quality rises.

We naturally produce hyaluronic acid, but its levels drop as we age, and that loss leads to fine lines and volume dips. This molecule can hold over 1,000 times its weight in water, keeping skin soft and plump. NEWEST restores that hydration, filling out lines and restoring youthful volume.

NEWEST by Mastelli Synergy Formulation Diagram

Why PN‑HPT™ Sets NEWEST Apart

PN‑HPT™ stands for Polynucleotide – Highly Purified Technology. It’s crafted through Mastelli’s patented HPT™ process, refined over 70 years of research. From fish selection to final batch testing, every step meets strict pharmaceutical standards in Italy. No other polynucleotide matches its purity or consistency.

Moreover, this isn’t marketing hype. PN‑HPT™ backs more than 100 published clinical studies. Both PLINEST® and NEWEST® rely on this original formula, trusted worldwide in aesthetic medicine. When you choose NEWEST at Cocoon, you get proven science, safe skin renewal, and results that last.

PN‑HPT™ - polynucleotides

How It Works

Numbing cream will be applied on the treatment area prior to the injections. This will significantly reduce the discomfort you may feel during the procedure. Plinest and Newest can be injected either with needles or blunt cannula. The use of blunt cannula can further reduce the discomfort and downtime post procedure.

During your session, a specialist uses tiny injections to place gel under the skin. First, polynucleotides signal fibroblasts to build collagen and elastin. Next, hyaluronic acid locks in moisture and plumps your skin. Then, mannitol shields the formula from break‑down and extends results. You may feel a mild pinch, but numbing cream keeps you comfortable. Best of all, downtime is minimal.

What to Expect of NEWEST by Mastelli

After your first visit, you might see slight redness or swelling. However, it clears within a few hours. Over the next two to three weeks, skin firmness and radiance improve noticeably. Additionally, a three‑session plan spaced 14–21 days apart amplifies results. By six weeks, a balanced, youthful glow emerges. Furthermore, most clients enjoy refreshed skin for six to nine months.

The results of NEWEST® by Mastelli can personally vary and are not permanent.

Who Should Try It

NEWEST suits adults with dry, dull, or aging skin. It works beautifully on the face, neck, and décolleté. Moreover, it tackles fine lines, large pores, scars, and uneven tone. If you seek natural, subtle rejuvenation without surgery, this treatment fits perfectly. In addition, anyone over 18 can benefit from its gentle yet powerful effects.

Is NEWEST by Mastelli Safe?

All treatments at Cocoon Medical Spa are done by licensed experts. NEWEST meets strict CE and pharmaceutical standards. Moreover, over 100 clinical studies confirm its safety and performance. Most clients experience only mild redness that clears quickly. Rare bruising fades within days. You’re in safe hands with our trained team.

Benefits & Results You’ll Notice

  • Skin feels smoother and softer in days.

  • Radiance and firmness improve over weeks.

  • Fine lines and dehydration visibly reduce.

  • Collagen support leads to a plumper, youthful glow.

Aftercare Tips

  1. Avoid touching treated areas for 24 hours.
  2. Skip saunas, hot showers, and intense workouts.
  3. Stay out of direct sun and tanning beds for two days.
  4. Refrain from alcohol and heavy makeup on treatment day.
  5. Use a gentle moisturizer and SPF every morning.

Following these tips ensures better results and reduces irritation.

Ready to glow?

The NEWEST by Mastelli treatment at Cocoon Medical Spa offers hydration, regeneration, and radiance in one session. Backed by decades of research and over 100 clinical studies, it restores your skin naturally and safely. Ready to glow? Book your appointment today and experience a fresher, firmer you.

BOOK NOW

You can also book a complimentary consultation by
emailing: info@cocoonmedicalspa.com or
WhatsApp: +62 811 388 815