NEWEST is a patented injectable gel from Mastelli Aesthetic in Italy. It combines PN‑HPT™ polynucleotides, hyaluronic acid, and mannitol in one precise formula. Together, these elements lock in moisture, power up your skin’s renewal, and shield against damage. In fact, hyaluronic acid boosts PN‑HPT™’s fibroblast stimulation by 20%, while mannitol slows HA breakdown by 30%.
Polynucleotide treatments have long helped medical healing, and now aesthetics benefit too. Mastelli sources DNA from selectively bred trout. Once injected into the dermis, these fragments spark collagen and elastin production at a cellular level. As a result, tissue regeneration improves and overall skin quality rises.
We naturally produce hyaluronic acid, but its levels drop as we age, and that loss leads to fine lines and volume dips. This molecule can hold over 1,000 times its weight in water, keeping skin soft and plump. NEWEST restores that hydration, filling out lines and restoring youthful volume.