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A woman in her sixties lies back with her eyes closed while gloved hands gently prepare the skin of her face.

Salmon DNA Skin Booster

Better skin. Same face.

Some skin concerns have nothing to do with volume or lines. Skin can simply look tired, feel dry, or lose its smoothness and bounce. Over a short course, your doctor places purified salmon DNA and hyaluronic acid into the skin through fine injections, so it can become better hydrated, then smoother and more elastic.

Gloved hands at Cocoon place a fine Salmon DNA injection into the side of the neck

How it works: working with your skin, not against it

Polynucleotides are small, purified fragments of salmon DNA, made with PN-HPT™, Polynucleotide Highly Purified Technology. They work with your skin’s own repair process and may encourage your fibroblasts, the cells that keep collagen and elastin in order. Alongside them, hyaluronic acid draws water into the skin.

Mannitol, an antioxidant, slows the formula’s breakdown so it lasts longer in the skin.

This is not a volumising filler. It does not change your shape. It improves the quality of the skin itself.

Where it can be used

Face, Around the eyes, Cheeks, Around the mouth, Neck, Décolletage

What to expect

  1. Within days

    Your skin may feel more hydrated.

  2. Over the weeks of a course

    Texture and fine lines take longer to change. Your doctor may adjust the course to your skin.

  3. Day 1 to 3

    Small bumps, redness, tenderness or mild swelling usually pass, and any bruising fades gradually.

  4. After your course

    The change can last six to nine months.

Results vary, and your doctor will tell you what to expect for your own skin.

Fine lines on a cheek before a polynucleotide skin booster, in Mastelli’s photograph
The same cheek after it
Image: Mastelli (Newest). Not a Cocoon client.

Your visit, step by step

Into the skin of the neck, below the jaw. Six seconds, filmed at Cocoon, no sound.
  1. Before

    • Tell your doctor what you take, including blood thinners, and about previous skin treatments
    • Leave a few days before an important event, as bumps or bruising may still show
    • Skip alcohol the day before, as it can increase bruising
    • Keep taking prescribed medicine unless its prescriber says to stop
    • Arrive with clean skin and no makeup
  2. The day

    Your skin is cleansed and numbed with a cream first. The injections are small and many, each leaves a tiny raised point, and the session takes under an hour. The points start to settle within several hours.

  3. Your first two weeks

    Day 1
    Mild redness, tenderness or swelling, and skin that feels dry or tight. No makeup for at least 12 hours
    First 24 hours
    No touching or massage of the treated areas, and no alcohol
    First 1 to 2 days
    No heavy exercise, saunas, hot showers, direct sun or tanning beds
    Days 2 to 3
    Swelling often peaks, and small bumps, dryness or light peeling can show. Use mild, hydrating products only
    Days 4 to 5
    Most redness and sensitivity settle, and the skin feels smoother. A bruise may still show
    Days 6 to 7
    Most swelling and flaking have gone. Moisturiser, serums and a physical sunscreen can return
    Two weeks
    Redness, bruising and swelling have usually cleared, and your full routine can come back gradually
  4. Aftercare

    • Use a mild moisturiser and SPF every morning, and keep out of direct sun
    • No scrubs or exfoliating acids for a few days
    • No AHAs, BHAs or retinoids for at least 7 days, or as your doctor advises
    • Contact us if anything unexpected develops

Questions people ask

Skin that looks rested, not changed.

Start with a consultation. Your doctor will look at your skin up close and tell you honestly what a Skin Booster course can do for it.

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